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KMID : 1134819970260020314
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Journal of the Korean Society of Food Science and Nutrition
1997 Volume.26 No. 2 p.314 ~ p.318
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Effects of Meju Powder Supplementation on lipid Metabolism in Rats Fed Hypercholesterolemic Diet한국식품영양과학회지
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Kim Jong-Dai
Lee Young-Il
Kim Bok-Ran
Choi Young-Soon
Lee Sang-Young
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Abstract
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This study was performed to examine the effects of Meju supplementation to high cholesterol diet on lipid metabolism in rats. Male Sprague-Dawley rats were divided into two groups(Steamed soybean, Meju) and were fed with 0.5% cholesterol diet. Serum and liver lipid profiles and fecal bile acids excretion were examined after four weeks of experimental diet. Food intake, weight gain and liver weight were not significantly different between the two groups. Total cholesterol concentrations in serum was significantly lower in Meju group compared to steamed soybean group(p＜0.05). HDL-cholesterol, triglyceride, phospholipids and nonestrified fatty acid concentrations in serum were not significantly different between the two groups. Cholesterol, triglyceride, and phospholipids concentrations in liver were not significantly different between the two groups. Fecal bile acid excretion were markedly higher in Meju groups than the group fed steamed soybean(p＜0.05). These results suggest that the cholesterol lowering effect by Meju supplementation might be resulted from the modulation of fecal bile acid excretion in rats.
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KEYWORD
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Meju, lipid metabolism, fecal bile acid
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